PigsPrescription Medicines

Porcilis PRRS Lyophilisate and Solvent for Injection

£16.70 - £122.43(exc VAT)£20.04 - £146.92(inc VAT)

Porcilis PRRS is a live attenuated lyophilised vaccine containing per dose (2 ml IM or 0.2 ml ID) 104.0 TCID50 to 106.3 TCID50* of PRRS virus strain DV to be reconstituted with Diluvac Forte containing 75 mg/ml dl-α-tocopherol acetate to a suspension for injection. *tissue culture infective dose 50 %

Used for active immunisation of clinically healthy pigs in a PRRS virus contaminated environment, to reduce viraemia caused by infection with European strains of PRRS virus.

For finishing pigs, the respiratory system is most relevant. A significant improvement of rearing results (reduced morbidity due to PRRS infection, and a better daily growth and feed conversion) until the end of the finishing period was observed in vaccinated pigs during field trials, particularly in piglets vaccinated at 6 weeks of age.

For breeding pigs, the effect of the virus on the reproductive system is most relevant. A significant improvement of the reproductive performance in PRRS virus contaminated environments and a reduction of transplacental virus transmission after challenge was observed in vaccinated pigs.

The objective of vaccination with Porcilis PRRS lies in obtaining a homogenous and high immune status against PRRS virus in a herd. Immunity has been demonstrated via challenge at 28 days post vaccination. A duration of immunity of at least 24 weeks has been demonstrated.

Legal Category: POM-V

Dosage

Reconstitute the vaccine with the adjuvanting diluent supplied (use only Diluvac Forte). Inject a few ml of diluent into the vaccine vial and shake gently until the vaccine is completely dissolved. Then transfer the concentrated vaccine to the rest of the diluent and mix well.

Intramuscular injection: 2 ml in the neck area behind the ear.

Intradermal application: 0.2 ml on the top or to the left or right side of the neck, or along the muscles of the back, using an intradermal device. A small, transient, intradermal lump observed after the intradermal application is indicative of the appropriate vaccination technique.

Vaccination scheme

A single dose is given to pigs from 2 weeks of age onwards.

Finishing pigs: A single vaccination is sufficient for protection until slaughter.

Breeding pigs: For gilts a (re)vaccination 2-4 weeks before mating is recommended.

To maintain a high and homogeneous level of immunity, revaccination at regular intervals is recommended, either before each next gestation or at random at 4 month intervals. Pregnant sows should only be vaccinated after previous exposure to European PRRS virus.

It is advised to vaccinate all target pigs within a herd from the earliest recommended age onwards.

Maternally derived antibodies may interfere with the response to vaccination.

Newly introduced PRRS virus-naïve animals (e.g. replacement gilts from PRRS virus-negative herds) should be vaccinated prior to pregnancy.

The vaccine can be used during lactation.

The vaccine may be reconstituted shortly before vaccination for simultaneous use with Porcilis M Hyo in finishing pigs from 4 weeks of age. A single dose (2ml) of porcilis PRRS mixed woth Porcilis M Hyo is given intramuscularly in the neck. Use sterile syringes and needles or clean intradermal equipment.

See packaging insert for further details.

Withdrawal Period: Zero days.

Contra Indications

Do not use in herds where the prevalence of European PRRS virus has not been established through reliable diagnostic methods.

Systemic or local reactions may be observed after vaccination. After intramuscular vaccination a transient hyperthermia may occur. In rare cases the vaccination can evoke hypersensitivity reactions such as dyspnoea, hyperaemia, decubitus, tremor, excitation and vomiting. These signs normally disappear spontaneously and totally within a few minutes after vaccination, however in very rare cases fatal anaphylactic reactions have occurred. A small firm intradermal lump (1.5 cm in diameter maximally) observed after the intradermal application is indicative of the appropriate vaccination technique. This dermal lump is generally seen for less than 14 days but may occasionally persist for 29 days or longer.

The effects seen after a ten-fold overdose of vaccine virus and a two-fold overdose of diluent were similar to those seen after a single dose of vaccine.

PRRS virus-naïve gilts and sows should not be vaccinated during pregnancy, as this can have negative effects. Vaccination during pregnancy is safe when it is performed in gilts and sows which are already immunized against European PRRS virus via vaccination or field infection.

Interactions

Safety and efficacy data for intramuscular injection are available in finishing pigs from 4 weeks of age onwards, which demonstrate that this vaccine can be mixed with Porcilis M Hyo. The product literature of Porcilis M Hyo should also be consulted before administration of the mixed product. No information is available on the safety and efficacy of this vaccine when used with any other veterinary medicinal product except the product mentioned above. No information is available on the safety and efficacy of the use of Porcilis PRRS mixed with Porcilis M.Hyo in breeding animals or during pregnancy. Do not mix with any other veterinary medicinal product, except the diluent supplied with the product or with Porcilis M Hyo.

Porcilis PRRS must only be used in PRRS virus contaminated herds, where prevalence of European PRRS virus has been established through reliable diagnostic virological methods. Care should be taken to avoid the introduction of the vaccine strain into an area where PRRS virus is not already present.

The vaccine virus may spread to pigs in contact during 5 weeks after vaccination.

The most common spreading route is via direct contact, but spreading via contaminated objects or via the air cannot be excluded. Care should be taken to avoid spread of vaccine virus from vaccinated animals to unvaccinated animals (e.g. naïve pregnant sows) that should remain free from PRRS virus.

Do not use in boars producing semen for seronegative herds, as PRRS virus may be excreted in semen for many weeks. No data are available on the safety of the vaccine for the reproductive performance in boars. Do not use in herds where a PRRS eradication programme based on serology has been adopted.

Intramuscular or intradermal administration of Porcilis PRRS results in the production of specific antibodies and active immunisation against infection caused by European strains of Porcine Reproductive and Respiratory Syndrome virus. Immunity is enhanced by the adjuvant dl-α-tocopherol acetate included in the diluent for reconstitution.

On the basis of antibodies induced by vaccination, it is not possible to discriminate vaccinated animals from those naturally infected with European strains of PRRS virus.

Size: 10, 25, 50 or 100 doses PRRS with 20, 50, 100 or 200 ml of Diluvac Forte.

NOAH Datasheet

For the most up to date information about this product please look up the Summary of Product Characteristics (SPC) on the VMD webpage Product Information Database.

  • 10 dosePrice: £16.70(exc VAT)
    POM-V
    1. This medicine is classified POM-V. York Vet Supplies has suitably qualified personnel who can dispense this item. In order to process your order, we will require you to post the original prescription from your Vet to us. Please tick to confirm that you understand prescription only item(s) will only be dispatched receipt of a valid copy of your prescription.
  • 25 dosePrice: £31.67(exc VAT)
    POM-V
    1. This medicine is classified POM-V. York Vet Supplies has suitably qualified personnel who can dispense this item. In order to process your order, we will require you to post the original prescription from your Vet to us. Please tick to confirm that you understand prescription only item(s) will only be dispatched receipt of a valid copy of your prescription.
  • 50 dosePrice: £61.93(exc VAT)
    POM-V
    1. This medicine is classified POM-V. York Vet Supplies has suitably qualified personnel who can dispense this item. In order to process your order, we will require you to post the original prescription from your Vet to us. Please tick to confirm that you understand prescription only item(s) will only be dispatched receipt of a valid copy of your prescription.
  • 100 dosePrice: £122.43(exc VAT)
    POM-V
    1. This medicine is classified POM-V. York Vet Supplies has suitably qualified personnel who can dispense this item. In order to process your order, we will require you to post the original prescription from your Vet to us. Please tick to confirm that you understand prescription only item(s) will only be dispatched receipt of a valid copy of your prescription.
Porcilis PRRS Lyophilisate and Solvent for Injection
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