Advantix Spot-on Solution for Dogs

£37.25 - £37.25 (exc VAT)

£44.70 - £44.70 (inc VAT)

A clear yellowish to brownish, solution containing imidacloprid and permethrin as active substances and 1.0 mg/ml butylhydroxytoluene (E321) as an antioxidant. The product is presented in a single use plastic pipette for dermal (spot-on) treatment in dogs. Each tube contains 100mg/ml Imidacloprid and 500mg/ml Permethrin.

For the treatment and prevention of flea (Ctenocephalides canis, Ctenocephalides felis) infestations in dogs only.

Fleas on dogs are killed within one day following treatment. One treatment prevents further flea infestation for four weeks. The product can be used as part of a treatment strategy for flea allergy dermatitis (FAD).

For the treatment of biting lice (Trichodectes canis).

The product has a persistent acaricidal and repellent efficacy against tick infestations (Rhipicephalus sanguineus, Ixodes ricinus for four weeks, and Dermacentor reticulatus for three weeks).

Ticks already on the dog may not be killed within two days after treatment and may remain attached and visible. Therefore the removal of ticks already on the dog at the time of treatment is recommended, in order to prevent them from attaching and having a blood meal.

One treatment provides repellent (anti-feeding) activity against sand flies (Phlebotomus papatasi for two weeks and Phlebotomus perniciosus for three weeks), against mosquitoes (Aedes aegypti for two weeks and Culex pipiens for four weeks) and against stable flies (Stomoxys calcitrans) for four weeks.

Legal Category: POM-V


The recommended minimum dose is:

10 mg/kg body weight imidacloprid and 50 mg/kg body weight permethrin.

For dermal use only. Apply only to undamaged skin. For further information on dosing refer to the packaging insert.

To reduce re-infestation from emergence of new fleas it is recommended that all dogs in a household be treated. Other pet animals living in the same household should also be treated with a suitable product. To further aid in reducing environmental challenge, the additional use of a suitable environmental treatment against adult fleas and their developmental stages is recommended.

The product remains effective if the animal becomes wet. However, prolonged, intense exposure to water should be avoided. Do not shampoo until at least 2 weeks after application to optimise efficacy of the product.

In case of biting louse infestation, a further veterinary examination 30 days after treatment is recommended as some animals may require a second treatment.

The product may be used during pregnancy and lactation.

Contra Indications

Do not use on cats. This product is extremely poisonous to cats. Keep cats away from treated dogs until the application site is dry.

In the absence of available data, the product should not be used on puppies of less than 7 weeks of age or 1.5 kg of weight.

Do not use in cases of known hypersensitivity to the active substances or to any of the excipients.

Care should be taken to avoid the contents of the pipette coming into contact with the eyes or mouth of the recipient dogs. In particular, oral uptake due to the licking of the application site by treated or in-contact animals should be avoided.

Consult your veterinary surgeon before using the product on sick and debilitated dogs.

On very rare occasions reactions in dogs may include transient skin sensitivity (increased local itching, scratching and rubbing, hair loss and redness at the application site) or lethargy that are generally self-resolving.

In very rare cases dogs may show behaviour changes (agitation, restlessness, whining or rolling), gastro-intestinal symptoms (vomiting, diarrhoea, hypersalivation, diminished appetite) and neurological signs such as unsteady movement and twitching in dogs susceptible to the ingredient permethrin. These signs are generally transient and self-resolving.

Poisoning following inadvertent oral uptake in dogs is unlikely but may occur in very rare cases. In this event, neurological signs such as tremor and lethargy can occur. Treatment should be symptomatic. There is no known specific antidote.

There may be an attachment of single ticks, or bites by single sand flies or mosquitoes. For this reason, a transmission of infectious diseases by these parasites cannot be completely excluded if conditions are unfavourable. However, the product provides repellent (anti-feeding) activity against ticks, sand flies and mosquitoes, thus preventing the repelled parasites from taking a blood meal and reducing the risk of Canine Vector-Borne Disease (CVBD) transmission (e.g. borreliosis, rickettsiosis, ehrlichiosis, leishmaniosis). No adverse clinical signs were noted in healthy puppies or adult dogs exposed to 5x overdosage or for puppies whose mothers were treated with 3x overdosage of the product.

The solvent in Advantix Spot-on solution may stain certain materials including leather, fabrics, plastics and finished surfaces. Allow the application site to dry before permitting contact with such materials.

User Safety

Avoid contact between the product and skin, eyes or mouth. Do not eat, drink or smoke during application. Wash hands thoroughly after use. In case of accidental spillage on to skin, wash off immediately with soap and water.

People with known skin sensitivity may be particularly sensitive to this product. The predominant clinical symptoms that in extremely rare cases may be shown are transient sensory irritations of the skin like tingling, burning sensation or numbness.

If skin or eye irritation persists, or if the product is accidentally swallowed, obtain medical attention immediately and show the package insert to the physician.

Treated dogs should not be handled, especially by children, until the application site is dry. Recently treated dogs should not be allowed to sleep together with their owner, especially children.

Environmental Safety

The product should not be allowed to enter water courses, as this may be dangerous for fish and aquatic organisms.

Treated dogs must not under any circumstances be allowed to enter into any type of surface water for at least 48 hours after treatment.

Permethrin-containing products are toxic to honey bees.

Do not store above 30°C.

Size: 4 tube packs for dogs up to4kg, 4-10kg, 10-25kg, over 25kg

NOAH datasheet

For the most up to date information about this product please look up the Summary of Product Characteristics (SPC) on the VMD webpage Product Information Database

4 - 10 kg Price: £37.25 (exc VAT)

POM-V Declaration

10 - 25 kg Price: £37.25 (exc VAT)

POM-V Declaration


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